The St. Regis San Francisco hotel incorporates a forty-storey tower, as well as the historic Williams Building that was built in the early 20th century, The latter is home to the Remède Spa that offers a range of Laboratoire Remède treatments, whirlpools, steam rooms, saunas and infinity-edge swimming pool plus the signature restaurant Ame that serves New American cuisine. A second restaurant, Vitrine, serves light and seasonal fare. The hotel is adjacent to the San Francisco Museum of Modern Art, with restaurants, shopping and nightlife nearby. Many of the guest rooms and suites feature city views as well as a plasma-screens and mini-bars. All guests can take advantage of the renowned St. Regis Butler Service for any requests they may have, as well as The St. Regis Signature Bath Menu which is a delightful treat for the senses.
Accessible, ADA compliant guest rooms are available. They each feature a roll-in shower, visual fire alarm, doorbell notification device, telephone notification device, portable communications kits containing visual alarms and notification devices, mobility-accessible doors with at least 32 inches of clear door width, portable tub seats, TTY and televisions with closed captioning for the hearing-impaired. Other public areas such as reception desk, concierge desk, restaurant, valet parking, fitness centre, swimming pool and business centre are also wheelchair accessible.